Oral vs. subcutaneous (sq) administration of methotrexate is generally considered equivalent in rheumatoid arthritis (RA) treatment. However, the enhanced bioavailability of sq methotrexate may make this route of administration preferable to the oral route in certain patients.

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Subcutaneous vs. Oral Methotrexate: Which is Preferred in Rheumatoid Arthritis?

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Atacicept is a recombinant fusion protein that binds and neutralizes two molecules important for the maturation, proliferation, and survival of B cells: BLyS and APRIL.

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Early Safety Study of Atacicept Shows Promise in Rheumatoid Arthritis